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The National Reye's Syndrome Foundation
PO Box 829 - Bryan - OH 43506
1-800-233-7393
nrsf@reyessyndrome.org
Reye's Syndrome Awareness Month is September - our Ribbon Color is Process Blue.
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Reye's Syndrome, a deadly disease, strikes swiftly and can attack any child, teen, or adult without warning. All body organs are affected, with the liver and brain suffering most seriously.

While the cause and cure remain unknown, research has established a link between Reye's Syndrome and the use of aspirin and other salicylate containing medications, over the counter products, and topical use products.

In 1974, the National Reye's Syndrome Foundation was incorporated, becoming the first citizen group to generate a concerted, organized lay movement to eradicate Reye's Syndrome.

Save A Life; Learn about Reye's Syndrome

Facts You Need to Know About Reye's Syndrome:

Reye's Syndrome is a very serious disease. Children and adults develop Reye's Syndrome as they are getting over a viral illness, such as the flu or chicken pox. Reye's Syndrome usually affects people from infancy through young adulthood; however, no age group is immune. Although Reye's generally occurs when someone is recovering from a viral illness, it can develop three to five days after the onset of the illness. The disease's main targets are the liver and brain. Reye's Syndrome is non-contagious, and too often is misdiagnosed as encephalitis, meningitis, diabetes, poisoning, drug overdose, or sudden infant death.

Early diagnosis is crucial. Following a viral illness, individuals should be watched during the next two to three weeks.

Fact: No one is immune. Reye's affects all ages, both genders, and every race.

Fact: Reye's will generally follow a viral illness or upper respiratory infection, i.e., cold, flu, chicken pox, ear infection, etc.

Fact: Research figures show that 90 to 95 percent of Reye's Syndrome patients in the United States have taken aspirin during a preceding viral illness.

Early Diagnosis is Crucial

Fact: A fever need not be present.

Fact: Reye's Syndrome occurs year-round, not just during the winter months.

Fact: Reye's Syndrome runs its course within a matter of hours to just a few days.

Fact: Aspirin and salicylate containing medications do not have to be ingested to bring on Reye's. These medications only increase a person's chance of developing the disease.

Fact: A person diagnosed with Reye's Syndrome must be hospitalized and treatment begun immediately.

Influenza Virus

Remember...
Reye's Syndrome usually appears after a flu-like infection, upper respiratory infection, chicken pox, or other viral illness.

The early signs are:

* Continuous vomiting
* Listlessness
* Loss of energy
* Aggressiveness
* Confusion
* Irrational behavior

Medicines can mask symptoms.

Do not give your child aspirin
or anti-nausea medications.

Call your doctor immediately.
Reye's Syndrome is always
a medical emergency.

Abnormal Liver Tests: SGOT (SAT) and SGPT (ACT) strongly suggest a diagnosis of Reye's Syndrome.

Time is important! Early
diagnosis is VITAL.

Fast Treatment is Crucial!

Reye's syndrome should be suspected in anyone who vomits repeatedly. Call your doctor immediately if these symptoms develop. Voice your concern about Reye's Syndrome. If your physician is unavailable, take the person to an Emergency Room promptly. Two liver function tests (SGOT (SAT), SGPT (ACT)) can be done to determine the possibility of Reye's Syndrome. There is a 90% chance of recovery when the syndrome is treated in its earliest stages by physicians and nurses experienced in the treatment of Reye's.

Studies have shown that using aspirin or aspirin containing medications to treat the symptoms of viral illnesses increases the chance of developing Reye's Syndrome. If you or a member of your family have a viral illness, do not use aspirin or aspirin containing medications. In fact, you should consult your physician before you take any drugs to treat any viral illness such as the flu or chicken pox, particularly aspirin or anti-nausea.

The National Reye's Syndrome Foundation (NRSF), the U.S. Surgeon General, the Food and Drug Administration, the Centers for Disease Control, and the American Academy of Pediatrics recommend that aspirin and combination products containing aspirin not be taken by anyone under 19 years of age during fever-causing illnesses.

Aspirin is a part of the salicylate family of medicines. Another name for aspirin is acetylsalicylate; some drug labels may use the words acetylsalicylate, acetylsalicylic acid, salicylic acid, salicylate, etc., instead of the word aspirin. Currently, there is no conclusive data as to whether other forms of salicylates are associated with the development of Reye's Syndrome. Until further research has answered this question, the NRSF recommends that products containing any of these substances not be taken during episodes of viral infections.

The NRSF is a nonprofit, tax-exempt organization with affiliates located in 44 states. The NRSF has pioneered the movement to disseminate knowledge about the disease in an effort to aid in early diagnosis and also provides funds for research into the cause, cure, care, treatment, and prevention of Reye's Syndrome.

Early Diagnosis is  Crucial

What Is Reye's Syndrome?

Reye's Syndrome is a disease which affects all organs of the body, but most lethally the liver and the brain. Reye's Syndrome is a two-phase illness because it is almost always associated with a previous viral infection, such as influenza, cold, or chicken pox. Scientists do know that Reye's Syndrome is not contagious and the cause is unknown. Reye's Syndrome is often misdiagnosed as encephalitis, meningitis, diabetes, drug overdose, poisoning, Sudden Infant Death Syndrome, or psychiatric illness.

Reye's Syndrome tends to appear with greatest frequency during January, February, and March when influenza is most common. Cases are reported in every month of the year. An epidemic of flu or chicken pox is commonly followed by an increase in the number of cases of Reye's Syndrome.

When Reye's Syndrome develops, it typically occurs when a person is beginning to recover from a viral illness. Abnormal accumulations of fat begin to develop in the liver and other organs of the body, along with a severe increase of pressure in the brain. Unless diagnosed and treated successfully, death is common, often within a few days. A person's life depends upon early diagnosis. Statistics indicate an excellent chance of recovery when Reye's Syndrome is diagnosed and treated in its earliest stages. The later the diagnosis and treatment, the more severely reduced are chances for successful recovery and survival.

Stages of Reye's Syndrome:

  • Stage I:
    Persistent or continuous vomiting
    Signs of brain dysfunction:
    Listlessness
    Loss of pep and energy
    Drowsiness
  • Stage II:
    Personality changes:
    Irritability
    Aggressive behavior
    Disorientation:
    Confusion
    Irrational behavior
    Combative
    Delirium, convulsions, coma

Reye's Syndrome should be suspected in a person if this pattern or symptoms appear during or, most commonly, after a viral illness. Not all of the symptoms have to occur, nor do they have to be displayed in this order. Fever is not usually present. Many diseases have symptoms in common. Physicians and medical staff in emergency rooms who have not had experience in treating Reye's Syndrome may misdiagnose the disease. The symptoms of Reye's Syndrome in infants do not follow a typical pattern. For example, vomiting may be replaced with diarrhea, and they may display irregular breathing.


The Foundation's Top Objectives are:

... AWARENESS - to aid in early detection and educate the public and medical communities about the risk involved with using aspirin and other salicylates.

... SERVICE - to provide emotional support and guidance to families experiencing the trauma of Reye's Syndrome.

... RESEARCH - to support investigation into the disease's cause, management, treatment and prevention, as well as study its impact on survivors.


If this site has proved helpful to you, a donation from you would assist us in keeping this site up-to-date. To make a tax deductible donation to the National Reye's Syndrome Foundation, click here.

To become a member of the National Reye's Syndrome Foundation, click here.

Know that your donations and memberships allow us to continue spreading Awareness about Reye's Syndrome to new mom's, new medical professionals, caregivers, schools, daycare centers, churches, and immigrants, and to a global population who can now access this website. You make a difference, a life and death difference. -- Thank You.

Report A Case of Reye's Syndrome

Tylenol and Ibuprophen do not contain Salicylates and can be used as a fever reducer.
When taking any medication we recommend you check with your doctor first.

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