Welcome to The National Reye's Syndrome Foundation
National Reye's Syndrome Foundation

Reye's Syndrome, a deadly disease, strikes swiftly and can attack any child, teen, or adult without warning. All body organs are affected, with the liver and brain suffering most seriously. While the cause and cure remain unknown, research has established a link between Reye's Syndrome and the use of aspirin and other salicylate containing medications, over the counter products, and topical use products. In 1974, the National Reye's Syndrome Foundation, a health advocacy organization, was incorporated as a 501(c)3 charity, whose mission is to eradicate the incidence of Reye's Syndrome.

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Emergency Room Information: Printable Version
Emergency Room Information
Suspect Reye's in an Infant with:
  • Diarrhea, but not necessarily vomiting
  • Respiratory disturbances such as hyperventilation or apneic episodes, seizures and hypoglycemia are common
  • Elevated SGOT-SGPT (SAT-ACT) [usually 200 or more units] in the absence of jaundice

Suspect Reye's in a Patient with:
  • Unexpected vomiting following any viral illness such as a flu-like upper respiratory infection or chicken pox (usually no diarrhea)
  • Elevated SGOT-SGPT (SAT-ACT) [usually 200 or more units] in the absence of jaundice
  • Signs of disturbed brain function characterized by:
  • Lethargy
  • .......
  • Staring
  • .......
  • Stupor
  • .......
  • Agitated delirium
  • .......
  • Screaming
  • .......
  • Drug reaction-like behavior
  • .......
  • Extensor spasms
  • .......
  • Decerebrate rigidity
  • .......
  • Aspirin poisoning-like symptoms
  • .......
  • Coma


For Early Diagnosis:

* Vomiting, think Reye's
* Emergency SGOT-SGPT (SAT-ACT)
* Elevated blood NH3
* Hypoglycemia and hepatomegaly may be present


Differential Diagnosis:

* Meningitis
* Encephalitis
* Diabetes
* Drug Overdose
* Sudden Infant Death
* Toxic Ingestion
* Head Trauma
* Renal or Hepatic Failure
* Poisoning


Initial Treatment:

* 10% Glucose in maintenance salt solution
* Maintain airway and brain oxygen
* Consult a teaching hospital or children's hospital

© 1974 - 2011 National Reye's Syndrome Foundation, Inc. A 501(c)3 - All Rights Reserved